Aging Cell

Scope

Aging Cell welcome submissions in the following areas: -Genetics and functional genomics: mutations affecting longevity; gene homologies; organismal and cellular aging; gene manipulation. -Signaling and gene expression: mechanisms linking age-associated changes with phenotypes and physiology; intracellular signaling; interactions between cells and tissues; hormonal, immune, and inflammatory systems. -Cell proliferation, aging and death: replicative senescence; apoptosis; telomere biology and other intrinsic and extrinsic influences; chronological cellular aging; phenotypes of aging cells. -Cell stress and damage: extrinsic and intrinsic influences of free radicals on cells and tissues; free radical defense and damage; free radicals as signaling molecules; stress and aging. -Stem cells and aging: effects of age on stem cell generation; migration and homeostasis; stem cell-niche interactions; regulatory mechanisms. -Integrative physiology: outcomes of aging processes at organismal, cellular and molecular levels. -Biodemography and comparative studies: population and cross-species comparative studies. -New theories of aging and longevity: discussion at the broadest level of established and novel theories of aging and longevity.